It has been reported that health status and loneliness, respectively, are major factors influencing depression among older adults. Meanwhile, there is the possibility that health status indirectly affects depression via its close relationship with loneliness. With regard to this indirect effects, however, age-friendly environments can make differences by providing community resources which help to compensate weakness of declining physical function and limited social participation due to vulnerable health status of older adults. In this context, this study examined moderated mediation effects of age-friendly environments on the indirect path from subjective health status to depression through loneliness. 615 adults aged 50 years and over of ‘2017 age integration survey’conducted nationally by Ewha Institute for Age Integration Research(EIAIR) are analyzed. As a result, the tendency that poor subjective health status indirectly increased depression with mediated by loneliness was promoted in less age-friendly environments. Consequently, the efforts to improve environmental conditions of less age-friendly communities are required first to prevent of older adults’ depression caused by poor health status and loneliness.